VPS37A Rabbit polyclonal antibody

Size

£152.00

SKU:: A14159
Additional Names:: HCRP1|PQBP2|SPG53|VPS37A
Application:: ELISA, WB, IF, ICC
Molecular Weight:: 44kda
Species Reactivity:: Human
Purification:: Affinity Purified
Storage Conditions:: -20[o]C Avoid freeze/thaw cycles.
Supplier:: Abclonal
Host:: Rabbit
Reactivities:: Human, Mouse, Rat
Immunogen:: Recombinant protein (or fragment).This information is considered to be commercially sensitive.
Formulation:: Unmodified
Sequence:: MPDVPDAFPELSELSVSQLTDMNEQEEVLLEQFLTLPQLKQIITDKDDLVKSIEELARKNLLLEPSLEAKRQTVLDKYELLTQMKSTFEKKMQRQHELSESCSASALQARLKVAAHEAEEESDNIAEDFLEGKMEIDDFLSSFMEKRTICHCRRAKEEKLQQAIAMHSQFHAPL
Uniprot:: Q8NEZ2
Synonyms:: ESCRT-I complex subunit VPS37A;HCRP1;hepatocellular carcinoma-related protein 1;polyglutamine binding protein 2;PQBP2;SPG53;vacuolar protein sorting 37 homolog A;vacuolar protein sorting-associated protein 37A;VPS37A, ESCRT-I subunit
Extra Details:: This gene belongs to the VPS37 family, and encodes a component of the ESCRT-I (endosomal sorting complex required for transport I) protein complex, required for the sorting of ubiquitinated transmembrane proteins into internal vesicles of multivesicular bodies. Expression of this gene is downregulated in hepatocellular carcinoma, and mutations in this gene are associated with autosomal recessive spastic paraplegia-53. A related pseudogene has been identified on chromosome 5. Alternatively spliced transcript variants have been found for this gene.