TXNDC5 Rabbit polyclonal antibody

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£152.00

SKU:: A14152
Additional Names:: ENDOPDI|ERP46|HCC-2|HCC2|PDIA15|STRF8|TXNDC5|UNQ364
Application:: ELISA, WB, IHC-P, IF, ICC
Molecular Weight:: 48kDa
Species Reactivity:: Human
Purification:: Affinity Purified
Storage Conditions:: -20[o]C Avoid freeze/thaw cycles.
Supplier:: Abclonal
Host:: Rabbit
Reactivities:: Human, Mouse, Rat
Immunogen:: Recombinant protein (or fragment).This information is considered to be commercially sensitive.
Formulation:: Unmodified
Sequence:: MEDAKVYVAKVDCTAHSDVCSAQGVRGYPTLKLFKPGQEAVKYQGPRDFQTLENWMLQTLNEEPVTPEPEVEPPSAPELKQGLYELSASNFELHVAQGDHFIKFFAPWCGHCKALAPTWEQLALGLEHSETVKIGKVDCTQHYELCSGNQVRGYPTLLWFRDGKKVDQYKGKRDLESLREYVESQLQRTETGATETVTPSEAPVLAAEPEADKGTVLALTENNFDDTIAEGITFIKFYAPWCGHCKTLAPTWEELSKKEFPGLAGVKIAEVDCTAERNICSKYSVRGYPTLLLFRGGKKVSEHSGGRDLDSLHRFVLSQAKDEL
Uniprot:: Q8NBS9
Synonyms:: ENDOPDI;endoplasmic reticulum protein ERp46;endoplasmic reticulum resident protein 46;endothelial protein disulphide isomerase;epididymis secretory sperm binding protein;ER protein 46;ERP46;HCC-2;HCC2;PDIA15;protein disulfide isomerase family A, member 15;STRF8;thioredoxin domain containing 5 (endoplasmic reticulum);thioredoxin domain-containing protein 5;thioredoxin related protein;thioredoxin-like protein p46;UNQ364
Extra Details:: This gene encodes a member of the disulfide isomerase (PDI) family of endoplasmic reticulum (ER) proteins that catalyze protein folding and thiol-disulfide interchange reactions. The encoded protein has an N-terminal endoplasmic reticulum (ER)-signal sequence, three catalytically active thioredoxin domains and a C-terminal ER-retention sequence. Its expression is induced by hypoxia and its role may be to protect hypoxic cells from apoptosis. Alternative splicing results in multiple transcript variants. Read-through transcription also exists between this gene and the neighboring upstream BLOC1S5 gene.

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