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A13726

DOK5 Rabbit polyclonal antibody

Size

£152.00

SKU:
A13726
Additional Names:
C20orf180|DOK5|IRS-6|IRS6
Application:
ELISA, WB
Molecular Weight:
30kDa
Species Reactivity:
Human
Purification:
Affinity Purified
Storage Conditions:
-20[o]C 50% glycerol. Avoid freeze/thaw cycles.
Supplier:
Abclonal
Host:
Rabbit
Reactivities:
Mouse, Rat
Immunogen:
Recombinant protein (or fragment).This information is considered to be commercially sensitive.
Formulation:
Unmodified
Sequence:
LLQSVKNSMLQMKMSERAASLSTMVPLPRSAYWQHITRQHSTGQLYRLQDVSSPLKLHRTETFPAYRSEH
Uniprot:
Q9P104
Synonyms:
C20orf180;docking protein 5;downstream of tyrosine kinase 5;insulin receptor substrate 6;IRS-6;IRS6
Extra Details:
The protein encoded by this gene is a member of the DOK family of membrane proteins, which are adapter proteins involved in signal transduction. The encoded protein interacts with phosphorylated receptor tyrosine kinases to mediate neurite outgrowth and activation of the MAP kinase pathway. Unlike other DOK family proteins, this protein does not interact with RASGAP. This protein is up-regulated in patients with systemic sclerosis and is associated with fibrosis induced by insulin-like growth factor binding protein 5. Alternative splicing of this gene results in multiple transcript variants.
Shipping Conditions:
Blue Ice