A13087
A1CF Rabbit polyclonal antibody
Size
£152.00
- SKU:
- A13087
- Additional Names:
- A1CF|ACF|ACF64|ACF65|APOBEC1CF|ASP
- Application:
- ELISA, WB, IHC-P
- Molecular Weight:
- 65kDa
- Species Reactivity:
- Human
- Purification:
- Affinity Purified
- Storage Conditions:
- -20[o]C 50% glycerol. Avoid freeze/thaw cycles.
- Supplier:
- Abclonal
- Host:
- Rabbit
- Reactivities:
- Human, Mouse, Rat
- Immunogen:
- Recombinant protein (or fragment).This information is considered to be commercially sensitive.
- Formulation:
- Unmodified
- Sequence:
- APPERGCEIFIGKLPRDLFEDELIPLCEKIGKIYEMRMMMDFNGNNRGYAFVTFSNKVEAKNAIKQLNNYE
- Uniprot:
- Q9NQ94
- Synonyms:
- ACF;ACF64;ACF65;apo-B RNA editing protein;apobec-1 complementation factor (ACF) (ASP);APOBEC-1 stimulating protein;APOBEC1 complementation factor;APOBEC1-stimulating protein;APOBEC1CF;ASP
- Extra Details:
- Mammalian apolipoprotein B mRNA undergoes site-specific C to U deamination, which is mediated by a multi-component enzyme complex containing a minimal core composed of APOBEC-1 and a complementation factor encoded by this gene. The gene product has three non-identical RNA recognition motifs and belongs to the hnRNP R family of RNA-binding proteins. It has been proposed that this complementation factor functions as an RNA-binding subunit and docks APOBEC-1 to deaminate the upstream cytidine. Studies suggest that the protein may also be involved in other RNA editing or RNA processing events. Several transcript variants encoding a few different isoforms have been found for this gene.
- Shipping Conditions:
- Blue Ice