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A12814

Olig2 Rabbit polyclonal antibody

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£152.00

SKU:
A12814
Additional Names:
BHLHB1|bHLHe19|Olig2|OLIGO2|PRKCBP2|RACK17
Application:
ELISA, WB, IHC-P
Molecular Weight:
35kda
Species Reactivity:
Human
Purification:
Affinity Purified
Storage Conditions:
-20[o]C Avoid freeze/thaw cycles.
Supplier:
Abclonal
Host:
Rabbit
Reactivities:
Human, Mouse, Rat
Immunogen:
Synthetic peptide. This information is considered to be commercially sensitive.
Formulation:
Unmodified
Sequence:
MDSDASLVSSRPSSPEPDDLFLPARSKGSSGSAFTGGTVSSSTPSDCPPELSAELRGAMGSAGAHPGDKLGGSGFKSSSS
Uniprot:
Q13516
Synonyms:
basic domain, helix-loop-helix protein, class B, 1;BHLHB1;bHLHe19;class B basic helix-loop-helix protein 1;class E basic helix-loop-helix protein 19;human protein kinase C-binding protein RACK17;OLIGO2;oligodendrocyte lineage transcription factor 2;oligodendrocyte transcription factor 2;oligodendrocyte-specific bHLH transcription factor 2;PRKCBP2;protein kinase C-binding protein 2;Protein kinase C-binding protein RACK17;RACK17
Extra Details:
This gene encodes a basic helix-loop-helix transcription factor which is expressed in oligodendroglial tumors of the brain. The protein is an essential regulator of ventral neuroectodermal progenitor cell fate. The gene is involved in a chromosomal translocation t(14;21)(q11.2;q22) associated with T-cell acute lymphoblastic leukemia. Its chromosomal location is within a region of chromosome 21 which has been suggested to play a role in learning deficits associated with Down syndrome.
Shipping Conditions:
Blue Ice