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A12732

LSM1 Rabbit polyclonal antibody

Size

£152.00

SKU:
A12732
Additional Names:
CASM|LSM1|YJL124C
Application:
ELISA, WB, IF, ICC
Molecular Weight:
17kDa
Species Reactivity:
Human
Purification:
Affinity Purified
Storage Conditions:
-20[o]C 50% glycerol. Avoid freeze/thaw cycles.
Supplier:
Abclonal
Host:
Rabbit
Reactivities:
Human, Mouse
Immunogen:
Recombinant protein (or fragment).This information is considered to be commercially sensitive.
Formulation:
Unmodified
Sequence:
MNYMPGTASLIEDIDKKHLVLLRDGRTLIGFLRSIDQFANLVLHQTVERIHVGKKYGDIPRGIFVVRGENVVLLGEIDLEKESDTPLQQVSIEEILEEQRVEQQTKLEAEKLKVQALKDRGLSIPRADTLDEY
Uniprot:
O15116
Synonyms:
cancer-associated Sm protein;Cancer-associated Sm-like;cancer-associated Sm-like protein;CASM;LSM1 homolog, U6 small nuclear RNA associated;LSM1 mRNA degradation associated;LSM1-like protein U6 small nuclear RNA associated;LSM1, U6 small nuclear RNA associated;small nuclear ribonuclear CaSm;U6 snRNA-associated Sm-like protein LSm1;YJL124C
Extra Details:
This gene encodes a member of the LSm family of RNA-binding proteins. LSm proteins form stable heteromers that bind specifically to the 3'-terminal oligo(U) tract of U6 snRNA and may play a role in pre-mRNA splicing by mediating U4/U6 snRNP formation. Increased expression of this gene may play a role in cellular transformation and the progression of several malignancies including lung cancer, mesothelioma and breast cancer. Alternatively spliced transcript variants have been observed for this gene, and a pseudogene of this gene is located on the short arm of chromosome 9.
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