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A12702

ERCC3 Rabbit polyclonal antibody

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£152.00

SKU:
A12702
Additional Names:
BTF2|ERCC3|GTF2H|RAD25|Ssl2|TFIIH|TTD2|XPB
Application:
ELISA, WB
Molecular Weight:
89kDa
Species Reactivity:
Human
Purification:
Affinity Purified
Storage Conditions:
-20[o]C 50% glycerol. Avoid freeze/thaw cycles.
Supplier:
Abclonal
Host:
Rabbit
Reactivities:
Human, Mouse, Rat
Immunogen:
Recombinant protein (or fragment).This information is considered to be commercially sensitive.
Formulation:
Unmodified
Sequence:
CPMSPEFYREYVAIKTKKRILLYTMNPNKFRACQFLIKFHERRNDKIIVFADNVFALKEYAIRLNKPYIYGPTSQGERMQILQNFKHNPKINTIFISKVGDTSFDLPEANVLIQISSHGGSRRQEAQRLGRVLRAKKGMVAEEYNAFFYSLVSQDTQEMAYSTKRQRFLVDQGYSFKVITKLAGMEEEDLAFSTKEEQQQLLQKVLAATDLDAEEEVVAGEFGSRSSQASRRFGTMSSMSGADDTVYMEYHSSRSKAPSKHVHPLFKRFRK
Uniprot:
P19447
Synonyms:
basic transcription factor 2 89 kDa subunit;BTF2;BTF2 p89;DNA excision repair protein ERCC-3;DNA repair helicase;DNA repair protein complementing XP-B cells;excision repair cross-complementation group 3;excision repair cross-complementing rodent repair deficiency, complementation group 3;general transcription and DNA repair factor IIH helicase subunit XPB;GTF2H;RAD25;Ssl2;TFIIH;TFIIH 89 kDa subunit;TFIIH basal transcription factor complex 89 kDa subunit;TFIIH basal transcription factor complex helicase XPB subunit;TFIIH p89;TFIIH subunit XPB;TTD2;xeroderma pigmentosum group B-complementing protein;xeroderma pigmentosum, complementation group B;XPB
Extra Details:
This gene encodes an ATP-dependent DNA helicase that functions in nucleotide excision repair. The encoded protein is a subunit of basal transcription factor 2 (TFIIH) and, therefore, also functions in class II transcription. Mutations in this gene are associated with Xeroderma pigmentosum B, Cockayne's syndrome, and trichothiodystrophy. Alternative splicing results in multiple transcript variants.
Shipping Conditions:
Blue Ice