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A1238

CD3D Rabbit polyclonal antibody

Size

£152.00

SKU:
A1238
Additional Names:
CD3-DELTA|CD3D|CD3DELTA|IMD19|T3D
Application:
ELISA, WB, IHC-P, IF, ICC
Molecular Weight:
19kDa
Species Reactivity:
Human
Purification:
Affinity Purified
Storage Conditions:
-20[o]C Avoid freeze/thaw cycles.
Supplier:
Abclonal
Host:
Rabbit
Reactivities:
Human, Rat
Immunogen:
Recombinant protein (or fragment).This information is considered to be commercially sensitive.
Formulation:
Unmodified
Sequence:
FKIPIEELEDRVFVNCNTSITWVEGTVGTLLSDITRLDLGKRILDPRGIYRCNGTDIYKDKESTVQVHYRMCQSCVELDPATVA
Uniprot:
P04234
Synonyms:
CD3 antigen, delta subunit;CD3 delta;CD3-DELTA;CD3d antigen, delta polypeptide (TiT3 complex);CD3d molecule, delta (CD3-TCR complex);IMD19;OKT3, delta chain;T-cell receptor T3 delta chain;T-cell surface glycoprotein CD3 delta chain;T3D
Extra Details:
The protein encoded by this gene is part of the T-cell receptor/CD3 complex (TCR/CD3 complex) and is involved in T-cell development and signal transduction. The encoded membrane protein represents the delta subunit of the CD3 complex, and along with four other CD3 subunits, binds either TCR alpha/beta or TCR gamma/delta to form the TCR/CD3 complex on the surface of T-cells. Defects in this gene are a cause of severe combined immunodeficiency autosomal recessive T-cell-negative/B-cell-positive/NK-cell-positive (SCIDBNK). Two transcript variants encoding different isoforms have been found for this gene. Other variants may also exist, but the full-length natures of their transcripts has yet to be defined.
Shipping Conditions:
Blue Ice