AKR7A2 Rabbit polyclonal antibody

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£152.00

SKU:: A1227
Additional Names:: AFAR|AFAR1|AFB1-AR1|AKR7|AKR7A2
Application:: ELISA, WB
Molecular Weight:: 35kda
Species Reactivity:: Human
Purification:: Affinity Purified
Storage Conditions:: -20[o]C Avoid freeze/thaw cycles.
Supplier:: Abclonal
Host:: Rabbit
Reactivities:: Human, Mouse
Immunogen:: Recombinant protein (or fragment).This information is considered to be commercially sensitive.
Formulation:: Unmodified
Sequence:: VKIATKANPWDGKSLKPDSVRSQLETSLKRLQCPQVDLFYLHAPDHGTPVEETLHACQRLHQEGKFVELGLSNYASWEVAEICTLCKSNGWILPTVYQGMYNATTRQVETELFPCLRHFGLRFYAYNPLAGGLLTGKYKYEDKDGKQPVGRFFGNSWAETYRNRFWKEHHFEAIALVEKALQAAYGASAPSVTSAALRWMYHHSQLQGAHGDAVILGMSSLEQLEQNLAATEEGPLEPAVVDAFNQAWHLVAHECPNYFR
Uniprot:: O43488
Synonyms:: AFAR;AFAR1;AFB1 aldehyde reductase 1;AFB1-AR 1;AFB1-AR1;aflatoxin aldehyde reductase;aflatoxin B1 aldehyde reductase member 2;aflatoxin beta1 aldehyde reductase;AKR7;aldoketoreductase 7;epididymis secretory sperm binding protein Li 166mP;HEL-S-166mP;SSA reductase;succinic semialdehyde reductase
Extra Details:: The protein encoded by this gene belongs to the aldo/keto reductase (AKR) superfamily and AKR7 family, which are involved in the detoxification of aldehydes and ketones. The AKR7 family consists of 3 genes that are present in a cluster on the p arm of chromosome 1. This protein, thought to be localized in the golgi, catalyzes the NADPH-dependent reduction of succinic semialdehyde to the endogenous neuromodulator, gamma-hydroxybutyrate. It may also function as a detoxication enzyme in the reduction of aflatoxin B1 and 2-carboxybenzaldehyde. Alternative splicing results in multiple transcript variants.

Shipping Conditions:: Blue Ice