STIP1 Rabbit polyclonal antibody

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£152.00

SKU:: A1219
Additional Names:: HEL-S-94n|HOP|IEF-SSP-3521|P60|STI1|STI1L|STIP1
Application:: ELISA, WB, IHC-P
Molecular Weight:: 63kDa
Species Reactivity:: Human
Purification:: Affinity Purified
Storage Conditions:: -20[o]C Avoid freeze/thaw cycles.
Supplier:: Abclonal
Host:: Rabbit
Reactivities:: Human, Mouse, Rat
Immunogen:: Recombinant protein (or fragment).This information is considered to be commercially sensitive.
Formulation:: Unmodified
Sequence:: MEQVNELKEKGNKALSVGNIDDALQCYSEAIKLDPHNHVLYSNRSAAYAKKGDYQKAYEDGCKTVDLKPDWGKGYSRKAAALEFLNRFEEAKRTYEEGLKHEANNPQLKEGLQNMEARLAERKFMNPFNMPNLYQKLESDPRTRTLLSDPTYRELIEQLRNKPSDLGTKLQDPRIMTTLSVLLGVDLGSMDEEEEIATPPPPPPPKKETKPEPMEEDLPENKKQALKEKELGNDAYKKKDFDTALKHYDKAKELDPTNMTYITNQAAVYFEKGDYNKCRELCEKAIEVGRENREDYRQIA
Uniprot:: P31948
Synonyms:: epididymis secretory sperm binding protein Li 94n;HEL-S-94n;HOP;hsc70/Hsp90-organizing protein;Hsp70/Hsp90-organizing protein;IEF-SSP-3521;NY-REN-11 antigen;P60;renal carcinoma antigen NY-REN-11;STI1;STI1L;stress-induced-phosphoprotein 1;transformation-sensitive protein IEF SSP 3521
Extra Details:: STIP1 is an adaptor protein that coordinates the functions of HSP70 (see HSPA1A; MIM 140550) and HSP90 (see HSP90AA1; MIM 140571) in protein folding. It is thought to assist in the transfer of proteins from HSP70 to HSP90 by binding both HSP90 and substrate-bound HSP70. STIP1 also stimulates the ATPase activity of HSP70 and inhibits the ATPase activity of HSP90, suggesting that it regulates both the conformations and ATPase cycles of these chaperones (Song and Masison, 2005 [PubMed 16100115]).

Shipping Conditions:: Blue Ice