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A1155

TRIF / TICAM1 Rabbit polyclonal antibody

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£152.00

SKU:
A1155
Additional Names:
IIAE6|MyD88-3|PRVTIRB|TICAM-1|TRIF|TRIF / TICAM1
Application:
ELISA, WB
Molecular Weight:
75kDa
Species Reactivity:
Human
Purification:
Affinity Purified
Storage Conditions:
-20[o]C Avoid freeze/thaw cycles.
Supplier:
Abclonal
Host:
Rabbit
Reactivities:
Human, Mouse, Rat
Immunogen:
Recombinant protein (or fragment).This information is considered to be commercially sensitive.
Formulation:
Unmodified
Sequence:
RPIDGVSDWSQGCSLRSTGSPASLASNLEISQSPTMPFLSLHRSPHGPSKLCDDPQASLVPEPVPGGCQEPEEMSWPPSGEIASPPELPSSPPPGLPEVAP
Uniprot:
Q8IUC6
Synonyms:
IIAE6;MyD88-3;proline-rich, vinculin and TIR domain-containing protein B;PRVTIRB;putative NF-kappa-B-activating protein 502H;TICAM-1;TIR domain containing adaptor inducing interferon-beta;TIR domain-containing adapter molecule 1;TIR domain-containing adapter protein inducing IFN-beta;toll-interleukin-1 receptor domain-containing adapter protein inducing interferon beta;TRIF
Extra Details:
This gene encodes an adaptor protein containing a Toll/interleukin-1 receptor (TIR) homology domain, which is an intracellular signaling domain that mediates protein-protein interactions between the Toll-like receptors (TLRs) and signal-transduction components. This protein is involved in native immunity against invading pathogens. It specifically interacts with toll-like receptor 3, but not with other TLRs, and this association mediates dsRNA induction of interferon-beta through activation of nuclear factor kappa-B, during an antiviral immune response. Mutations in this gene are associated with encephalopathy, acute, infection-induced.
Shipping Conditions:
Blue Ice