POLR2A Rabbit polyclonal antibody

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£152.00

SKU:: A11181
Additional Names:: hRPB220|hsRPB1|NEDHIB|POLR2|POLR2A|POLRA|RPB1|RPBh1|RpIILS|RPO2|RPOL2
Application:: ChIP, ELISA, WB, IHC-P, IF, ICC
Molecular Weight:: 250 kDa
Species Reactivity:: Human
Purification:: Affinity Purified
Storage Conditions:: -20[o]C Avoid freeze/thaw cycles.
Supplier:: Abclonal
Host:: Rabbit
Reactivities:: Human, Mouse, Rat
Immunogen:: Synthetic peptide. This information is considered to be commercially sensitive.
Formulation:: Unmodified
Sequence:: MHGGGPPSGDSACPLRTIKRVQFGVLSPDELKRMSVTEGGIKYPETTEGGRPKLGGLMDPRQGVIERTGRCQTCAGNMTECPGHFGHIELAKPVFHVGFLVKTMKVLRCVCFFCSKLLVDSNNPKIKDILAKSKGQPKKRLTHVYDLCKGKNICEGGEEMDNKFGVEQPEGDEDLTKEKGHGGCGRYQPRIRRSGLELYAEWKHVNEDSQEKKILLSPERVHEIFKRISDEECFVLGMEPRYARPEWMIVTVLPVPPLSV
Uniprot:: P24928
Synonyms:: DNA-directed RNA polymerase II largest subunit, RNA polymerase II 220 kd subunit;DNA-directed RNA polymerase II subunit A;DNA-directed RNA polymerase II subunit RPB1;DNA-directed RNA polymerase III largest subunit;hRPB220;hsRPB1;NEDHIB;POLR2;POLRA;polymerase (RNA) II (DNA directed) polypeptide A, 220kDa;polymerase (RNA) II subunit A;RNA polymerase II subunit B1;RNA-directed RNA polymerase II subunit RPB1;RPB1;RPBh1;RpIILS;RPO2;RPOL2
Extra Details:: This gene encodes the largest subunit of RNA polymerase II, the polymerase responsible for synthesizing messenger RNA in eukaryotes. The product of this gene contains a carboxy terminal domain composed of heptapeptide repeats that are essential for polymerase activity. These repeats contain serine and threonine residues that are phosphorylated in actively transcribing RNA polymerase. In addition, this subunit, in combination with several other polymerase subunits, forms the DNA binding domain of the polymerase, a groove in which the DNA template is transcribed into RNA.

Shipping Conditions:: Blue Ice