Ambra1 Rabbit polyclonal antibody

Size

£152.00

SKU:: A1083
Additional Names:: Ambra1|DCAF3|WDR94
Application:: ELISA, WB, IHC-P, IF, ICC
Molecular Weight:: 130-150kDa
Species Reactivity:: Human
Purification:: Affinity Purified
Storage Conditions:: -20[o]C Avoid freeze/thaw cycles.
Supplier:: Abclonal
Host:: Rabbit
Reactivities:: Human, Mouse, Rat
Immunogen:: Recombinant protein (or fragment).This information is considered to be commercially sensitive.
Formulation:: Unmodified
Sequence:: GAAHTSSPQPSTSRGLLPEAGQLAERGLSPRTASWDQPGTPGREPTQPTLPSSSPVPIPVSLPSAEGPTLHCELTNNNHLLDGGSSRGDAAGPRGEPRNR
Uniprot:: Q9C0C7
Synonyms:: activating molecule in beclin-1-regulated autophagy;activating molecule in BECN1-regulated autophagy protein 1;autophagy/beclin-1 regulator 1;DCAF3;DDB1 and CUL4 associated factor 3;WD repeat domain 94;WDR94
Extra Details:: Enables GTPase binding activity and ubiquitin protein ligase binding activity. Involved in macroautophagy; positive regulation of phosphatidylinositol 3-kinase activity; and response to mitochondrial depolarisation. Located in cytosol. Colocalizes with mitochondrion. Biomarker of multiple system atrophy.