A10818
UBE2D2 Rabbit polyclonal antibody
Size
POA
- SKU:
- A10818
- Additional Names:
- E2(17)KB2|PUBC1|UBC4|UBC4/5|UBCH4|UBCH5B|UBE2D2
- Application:
- ELISA, WB
- Molecular Weight:
- 17kDa
- Species Reactivity:
- Human
- Purification:
- Affinity Purified
- Storage Conditions:
- -20[o]C 50% glycerol. Avoid freeze/thaw cycles.
- Supplier:
- Abclonal
- Host:
- Rabbit
- Reactivities:
- Human, Mouse, Rat
- Immunogen:
- Recombinant protein (or fragment).This information is considered to be commercially sensitive.
- Formulation:
- Unmodified
- Uniprot:
- P62837
- Synonyms:
- (E3-independent) E2 ubiquitin-conjugating enzyme D2;E2 ubiquitin-conjugating enzyme D2;E2(17)KB2;p53-regulated ubiquitin-conjugating enzyme 1;PUBC1;UBC4;UBC4/5;UBCH4;UBCH5B;ubiquitin carrier protein D2;ubiquitin conjugating enzyme E2D 2;ubiquitin-conjugating enzyme E2 D2;ubiquitin-conjugating enzyme E2-17 kDa 2;Ubiquitin-conjugating enzyme E2(17)KB 2;ubiquitin-conjugating enzyme E2D 2 (homologous to yeast UBC4/5);ubiquitin-protein ligase D2
- Extra Details:
- Regulated degradation of misfolded, damaged or short-lived proteins in eukaryotes occurs via the ubiquitin (Ub)-proteasome system (UPS). An integral part of the UPS system is the ubiquitination of target proteins and covalent linkage of Ub-containing proteins to form polymeric chains, marking them as targets for 26S proteasome-mediated degradation. Ubiquitination of proteins is mediated by a cascade of enzymes which includes E1 (ubiquitin activating), E2 (ubiquitin conjugating), and E3 (ubiquitin ligases) enzymes. This gene encodes a member of the E2 enzyme family. Substrates of this enzyme include the tumor suppressor protein p53 and peroxisomal biogenesis factor 5 (PEX5). Alternative splicing results in multiple transcript variants of this gene.
- Shipping Conditions:
- Blue Ice