RBM5 Rabbit polyclonal antibody

Size

£152.00

SKU:: A10788
Additional Names:: G15|H37|LUCA-15|LUCA15|RBM5|RMB5
Application:: ELISA, WB
Molecular Weight:: 120kDa
Species Reactivity:: Human
Purification:: Affinity Purified
Storage Conditions:: -20[o]C 50% glycerol. Avoid freeze/thaw cycles.
Supplier:: Abclonal
Host:: Rabbit
Reactivities:: Human, Mouse, Rat
Immunogen:: Recombinant protein (or fragment).This information is considered to be commercially sensitive.
Formulation:: Unmodified
Sequence:: MGSDKRVSRTERSGRYGSIIDRDDRDERESRSRRRDSDYKRSSDDRRGDRYDDYRDYDSPERERERRNSDRSEDGYHSDGDYGEHDYRHDISDERESKTIMLRGLPITITESDIREMMESFEGPQPADVR
Uniprot:: P52756
Synonyms:: G15;H37;LUCA-15;LUCA15;Protein G15;putative tumor suppressor LUCA15;renal carcinoma antigen NY-REN-9;RMB5;RNA-binding motif protein 5;RNA-binding protein 5
Extra Details:: This gene is a candidate tumor suppressor gene which encodes a nuclear RNA binding protein that is a component of the spliceosome A complex. The encoded protein plays a role in the induction of cell cycle arrest and apoptosis through pre-mRNA splicing of multiple target genes including the tumor suppressor protein p53. This gene is located within the tumor suppressor region 3p21.3, and may play a role in the inhibition of tumor transformation and progression of several malignancies including lung cancer.