A10682
CRTC2 Rabbit polyclonal antibody
Size
£152.00
- SKU:
- A10682
- Additional Names:
- CRTC2|TORC-2|TORC2
- Application:
- ELISA, WB
- Molecular Weight:
- 73kDa
- Species Reactivity:
- Human
- Purification:
- Affinity Purified
- Storage Conditions:
- -20[o]C Avoid freeze/thaw cycles.
- Supplier:
- Abclonal
- Host:
- Rabbit
- Reactivities:
- Human
- Immunogen:
- Recombinant protein (or fragment).This information is considered to be commercially sensitive.
- Formulation:
- Unmodified
- Sequence:
- ASNPRKFSEKIALQKQRQAEETAAFEEVMMDIGSTRLQAQKLRLAYTRSSHYGGSLPNVNQIGSGLAEFQSPLHSPLDSSRSTRHHGLVERVQRDPRRMVSPLRRYTRHID
- Uniprot:
- Q53ET0
- Synonyms:
- CREB-regulated transcription coactivator 2;TORC-2;TORC2;transducer of regulated cAMP response element-binding protein (CREB) 2;Transducer of regulated cAMP response element-binding protein 2
- Extra Details:
- This gene encodes a member of the transducers of regulated cAMP response element-binding protein activity family of transcription coactivators. These proteins promote the transcription of genes targeted by the cAMP response element-binding protein, and therefore play an important role in many cellular processes. Under basal conditions the encoded protein is phosphorylated by AMP-activated protein kinase or the salt-inducible kinases and is sequestered in the cytoplasm. Upon activation by elevated cAMP or calcium, the encoded protein translocates to the nucleus and increases target gene expression. Single nucleotide polymorphisms in this gene may increase the risk of type 2 diabetes. A pseudogene of this gene is located on the long arm of chromosome 5.
- Shipping Conditions:
- Blue Ice