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A10596

MARCH9 Rabbit polyclonal antibody

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£152.00

SKU:
A10596
Additional Names:
MARCH-IX|MARCH9|RNF179
Application:
ELISA, WB
Molecular Weight:
36kda
Species Reactivity:
Human
Purification:
Affinity Purified
Storage Conditions:
-20[o]C Avoid freeze/thaw cycles.
Supplier:
Abclonal
Host:
Rabbit
Reactivities:
Human
Immunogen:
Recombinant protein (or fragment).This information is considered to be commercially sensitive.
Formulation:
Unmodified
Sequence:
GTAGKSGPRNSRTGPTSGATSRPPAAQRMRTLLPQRCGYTILHLLGQLRPPDARSSSHSGREVVMRVTTV
Uniprot:
Q86YJ5
Synonyms:
E3 ubiquitin-protein ligase MARCH9;E3 ubiquitin-protein ligase MARCHF9;MARCH-IX;MARCH9;membrane associated ring finger 9;membrane-associated ring finger (C3HC4) 9;membrane-associated RING finger protein 9;membrane-associated RING-CH protein IX;RING finger protein 179;RING-type E3 ubiquitin transferase MARCH9;RING-type E3 ubiquitin transferase MARCHF9;RNF179
Extra Details:
MARCH9 is a member of the MARCH family of membrane-bound E3 ubiquitin ligases (EC 6.3.2.19). MARCH enzymes add ubiquitin (see MIM 191339) to target lysines in substrate proteins, thereby signaling their vesicular transport between membrane compartments. MARCH9 induces internalization of several membrane glycoproteins and directs them to the endosomal compartment (Bartee et al., 2004 [PubMed 14722266]; Hoer et al., 2007 [PubMed 17174307]).
Shipping Conditions:
Blue Ice