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A10492

NFKBIZ Rabbit polyclonal antibody

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£152.00

SKU:
A10492
Additional Names:
I-kappa-B-zeta|IkappaB-zeta|ikappaBzeta|ikB-zeta|IKBZ|INAP|MAIL|NFKBIZ
Application:
ELISA, WB
Molecular Weight:
64kDa
Species Reactivity:
Human
Purification:
Affinity Purified
Storage Conditions:
-20[o]C Avoid freeze/thaw cycles.
Supplier:
Abclonal
Host:
Rabbit
Reactivities:
Rat
Immunogen:
Recombinant protein (or fragment).This information is considered to be commercially sensitive.
Formulation:
Unmodified
Sequence:
MIVDKLLDDSRGGEGLRDAAGGCGLMTSPLNLSYFYGASPPAAAPGACDASCSVLGPSAPGSPGSDSSDFSSASSVSSCGAVESRSRGGARAERQPVEPHMGVGRQQRGPFQGVRVKNSVKELLLHIRSHKQKASGQAVDDFKTQGVNIEQFRELKNTVSYSGKRKGPDSLSDGPACKRPALLHSQFLTPPQTPTPGESMEDVHLNEPKQESSADLLQNI
Uniprot:
Q9BYH8
Synonyms:
I-kappa-B-zeta;Ikappa B-zeta variant 3;IkappaB-zeta;ikappaBzeta;ikB-zeta;IKBZ;IL-1 inducible nuclear ankyrin-repeat protein;INAP;MAIL;molecule possessing ankyrin repeats induced by lipopolysaccharide;NF-kappa-B inhibitor zeta;nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, zeta
Extra Details:
This gene is a member of the ankyrin-repeat family and is induced by lipopolysaccharide (LPS). The C-terminal portion of the encoded product which contains the ankyrin repeats, shares high sequence similarity with the I kappa B family of proteins. The latter are known to play a role in inflammatory responses to LPS by their interaction with NF-B proteins through ankyrin-repeat domains. Studies in mouse indicate that this gene product is one of the nuclear I kappa B proteins and an activator of IL-6 production. Two transcript variants encoding different isoforms have been found for this gene.
Shipping Conditions:
Blue Ice