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A10440

LMAN1 Rabbit polyclonal antibody

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£152.00

SKU:
A10440
Additional Names:
ERGIC-53|ERGIC53|F5F8D|FMFD1|gp58|LMAN1|MCFD1|MR60
Application:
ELISA, WB, IHC-P, IF, ICC
Molecular Weight:
55kDa
Species Reactivity:
Human
Purification:
Affinity Purified
Storage Conditions:
-20[o]C Avoid freeze/thaw cycles.
Supplier:
Abclonal
Host:
Rabbit
Reactivities:
Human, Mouse, Rat
Immunogen:
Recombinant protein (or fragment).This information is considered to be commercially sensitive.
Formulation:
Unmodified
Uniprot:
P49257
Synonyms:
endoplasmic reticulum-golgi intermediate compartment protein 53;ER-Golgi intermediate compartment 53 kDa protein;ERGIC-53;ERGIC53;F5F8D;FMFD1;gp58;intracellular mannose-specific lectin MR60;Lectin mannose-binding 1;MCFD1;MR60;protein ERGIC-53
Extra Details:
The protein encoded by this gene is a membrane mannose-specific lectin that cycles between the endoplasmic reticulum, endoplasmic reticulum-Golgi intermediate compartment, and cis-Golgi, functioning as a cargo receptor for glycoprotein transport. The protein has an N-terminal signal sequence, a calcium-dependent and pH-sensitive carbohydrate recognition domain, a stalk region that functions in oligomerization, a transmembrane domain, and a short cytoplasmic domain required for organelle targeting. Allelic variants of this gene are associated with the autosomal recessive disorder combined factor V-factor VIII deficiency.
Shipping Conditions:
Blue Ice