A10413
ZIP14 Rabbit polyclonal antibody
Size
£152.00
- SKU:
- A10413
- Additional Names:
- cig19|HCIN|HMNDYT2|LZT-Hs4|NET34|ZIP14
- Application:
- ELISA, WB, IHC-P, IF, ICC
- Molecular Weight:
- 54 kda
- Species Reactivity:
- Human
- Purification:
- Affinity Purified
- Storage Conditions:
- -20[o]C Avoid freeze/thaw cycles.
- Supplier:
- Abclonal
- Host:
- Rabbit
- Reactivities:
- Human, Mouse, Rat
- Immunogen:
- Synthetic peptide. This information is considered to be commercially sensitive.
- Formulation:
- Unmodified
- Sequence:
- HNFSEQSRIGSSELQEFCPTILQQLDSRACTSENQENEENEQTEEGRPSAVEVWGYGLLCVTVISLCSLLGASVVPFMKKTFYKRLLLYFIALAIGTLYSNALFQLIPEAFGFNPLEDYYVSKSAVVFGGFYLFFFTEKILKILLKQKNEHHHGHSHYASESLPSKKDQEEGVMEKLQNGDLDHMIPQHCSSELDGKAPM
- Uniprot:
- Q15043
- Synonyms:
- cig19;HCIN;HMNDYT2;LIV-1 subfamily of ZIP zinc transporter 4;LZT-Hs4;metal cation symporter ZIP14;NET34;solute carrier family 39 (metal ion transporter), member 14;solute carrier family 39 (zinc transporter), member 14;Solute carrier family 39 member 14;Zinc transporter ZIP14;ZIP14;zrt- and Irt-like protein 14;Zrt-, Irt-like protein 14
- Extra Details:
- This gene encodes a member of the the SLC39A family of divalent metal transporters that mediates the cellular uptake of manganese, zinc, iron, and cadmium. The encoded protein contains eight transmembrane domains, a histidine-rich motif, and a metalloprotease motif, and is expressed on the plasma membrane and the endocytic vesicle membrane. It is an important transporter of nontransferrin-bound iron and a critical regulator of manganese homeostasis. Naturally occurring mutations in this gene are associated with neurodegeneration with brain iron accumulation and early-onset parkinsonism-dystonia with hypermanganesemia.
- Shipping Conditions:
- Blue Ice