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A10380

CHMP2A Rabbit polyclonal antibody

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£152.00

SKU:
A10380
Additional Names:
BC-2|BC2|CHMP2|CHMP2A|VPS2|VPS2A
Application:
ELISA, WB
Molecular Weight:
37kDa
Species Reactivity:
Human
Purification:
Affinity Purified
Storage Conditions:
-20[o]C Avoid freeze/thaw cycles.
Supplier:
Abclonal
Host:
Rabbit
Reactivities:
Human
Immunogen:
Recombinant protein (or fragment).This information is considered to be commercially sensitive.
Formulation:
Unmodified
Sequence:
MDLLFGRRKTPEELLRQNQRALNRAMRELDRERQKLETQEKKIIADIKKMAKQGQMDAVRIMAKDLVRTRRYVRKFVLMRANIQAVSLKIQTLKSNNSMAQAMKGVTKAMGTMNRQLKLPQIQKIMMEFERQAEIMDMKEEMMNDAIDDAMGDEEDEEESDAVVSQVLDELGLSLTDELSNLPSTGGSLSVAAGGKKAEAAASALADADADLEERLKNLRRD
Uniprot:
O43633
Synonyms:
BC-2;BC2;charged multivesicular body protein 2a;CHMP2;chromatin modifying protein 2A;Chromatin-modifying protein 2a;putative breast adenocarcinoma marker (32kD);putative breast adenocarcinoma marker BC-2;vacuolar protein sorting-associated protein 2-1;VPS2;VPS2 homolog A;vps2-1;VPS2A
Extra Details:
CHMP2A belongs to the chromatin-modifying protein/charged multivesicular body protein (CHMP) family. These proteins are components of ESCRT-III (endosomal sorting complex required for transport III), a complex involved in degradation of surface receptor proteins and formation of endocytic multivesicular bodies (MVBs). Some CHMPs have both nuclear and cytoplasmic/vesicular distributions, and one such CHMP, CHMP1A (MIM 164010), is required for both MVB formation and regulation of cell cycle progression (Tsang et al., 2006 [PubMed 16730941]).
Shipping Conditions:
Blue Ice