MAN2A1 Rabbit polyclonal antibody

Size

£152.00

SKU:: A10227
Additional Names:: AMan II|GOLIM7|MAN2A1|MANA2|MANII
Application:: ELISA, WB
Molecular Weight:: 131-170kDa
Species Reactivity:: Human
Purification:: Affinity Purified
Storage Conditions:: -20[o]C Avoid freeze/thaw cycles.
Supplier:: Abclonal
Host:: Rabbit
Reactivities:: Human, Mouse, Rat
Immunogen:: Recombinant protein (or fragment).This information is considered to be commercially sensitive.
Formulation:: Unmodified
Sequence:: SNIVDIRKVYNREIAMKISSDIKSQNRFYTDLNGYQIQPRMTLSKLPLQANVYPMTTMAYIQDAKHRLTLLSAQSLGVSSLNSGQIEVIMDRRLMQDDNRGLEQGIQDNKITANLFRILLEKRSAVNTEEEKKSVSYPSLLSHITSSLMNHPVIPMANKFSSPTLELQGEFSPLQSSLPCDIHLVNLRTIQSKVGNGHSNEAALILHRKGFDCRFSSKGTGLFCSTTQGKILVQKLLNKFIVESLTPSSLSLMHSPPGTQNISEINLSPMEISTFRIQLR
Uniprot:: Q16706
Synonyms:: alpha-mannosidase 2;AMan II;Golgi alpha-mannosidase II;golgi integral membrane protein 7;GOLIM7;MANA2;MANII;Mannosidase alpha class 2A member 1;mannosidase, alpha type II;mannosyl-oligosaccharide 1,3-1,6-alpha-mannosidase
Extra Details:: This gene encodes a glycosyl hydrolase that localizes to the Golgi and catalyzes the final hydrolytic step in the asparagine-linked oligosaccharide (N-glycan) maturation pathway. Mutations in the mouse homolog of this gene have been shown to cause a systemic autoimmune disease similar to human systemic lupus erythematosus.