GSDMD (Full length+N terminal) Rabbit polyclonal antibody

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£152.00

SKU:: A10164
Additional Names:: 1810036L03Rik|DF5L|Dfna5l|GSDMD (Full Length+N terminal)|GsdmD-1|Gsdmdc1|M2-4
Application:: ELISA, WB, IF, ICC
Molecular Weight:: 35kDa/53kDa
Species Reactivity:: Mouse
Purification:: Affinity Purified
Storage Conditions:: -20[o]C Avoid freeze/thaw cycles.
Supplier:: Abclonal
Host:: Rabbit
Reactivities:: Human, Mouse, Rat
Immunogen:: Recombinant protein (or fragment).This information is considered to be commercially sensitive.
Formulation:: Unmodified
Uniprot:: Q9D8T2
Synonyms:: 1810036L03Rik;AW558049;DF5;DF5L;Dfn;Dfna5l;FKSG10;gasdermin domain containing 1;gasdermin domain-containing protein 1;gasdermin-D;gasderminD-1;GsdmD-1;Gsdmdc;Gsdmdc1;M2-4
Extra Details:: Enables phospholipid binding activity and wide pore channel activity. Involved in several processes, including defense response to bacterium; positive regulation of interleukin-1 beta production; and protein-containing complex assembly. Acts upstream of or within cellular response to extracellular stimulus. Located in cytosol; extracellular space; and plasma membrane. Part of NLRP3 inflammasome complex. Is expressed in several structures, including gut; liver; lung; metanephros; and spleen. Orthologous to human GSDMD (gasdermin D).