INPPL1 Rabbit polyclonal antibody

Size

£152.00

SKU:: A10115
Additional Names:: INPPL1|OPSMD|SHIP2
Application:: ELISA, WB
Molecular Weight:: 160kDa
Species Reactivity:: Human
Purification:: Affinity Purified
Storage Conditions:: -20[o]C Avoid freeze/thaw cycles.
Supplier:: Abclonal
Host:: Rabbit
Reactivities:: Human, Mouse, Rat
Immunogen:: Recombinant protein (or fragment).This information is considered to be commercially sensitive.
Formulation:: Unmodified
Sequence:: GLYAQPNQGLVCALLLPVEGEREPDPPDDRDASDGEDEKPPLPPRSGSTSISAPTGPSSPLPAPETPTAPAAESAPNGLSTVSHDYLKGSYGLDLEAVRGGASHLPHLTRTLATSCRRLHSEVDKVLSGLEILSKVFDQQSSPMVTRLLQQQNLPQTGEQELESLVLKLSVLKDFLSGIQKKALKALQDMSSTAPPAPQPSTRKAKTIPVQ
Uniprot:: O15357
Synonyms:: 51C protein;Inositol polyphosphate phosphatase-like protein 1;INPPL-1;OPSMD;phosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 2;protein 51C;SH2 domain-containing inositol 5'-phosphatase 2;SH2 domain-containing inositol-5'-phosphatase 2;SHIP-2;SHIP2
Extra Details:: The protein encoded by this gene is an SH2-containing 5'-inositol phosphatase that is involved in the regulation of insulin function. The encoded protein also plays a role in the regulation of epidermal growth factor receptor turnover and actin remodelling. Additionally, this gene supports metastatic growth in breast cancer and is a valuable biomarker for breast cancer.