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A10079

CD53 Rabbit polyclonal antibody

Size

£152.00

SKU:
A10079
Additional Names:
CD53|MOX44|TSPAN25
Application:
ELISA, WB
Molecular Weight:
35-45kDa
Species Reactivity:
Human
Purification:
Affinity Purified
Storage Conditions:
-20[o]C Avoid freeze/thaw cycles.
Supplier:
Abclonal
Host:
Rabbit
Reactivities:
Human, Mouse
Immunogen:
Recombinant protein (or fragment).This information is considered to be commercially sensitive.
Formulation:
Unmodified
Sequence:
AILLFVYEQKLNEYVAKGLTDSIHRYHSDNSTKAAWDSIQSFLQCCGINGTSDWTSGPPASCPSDRKVEGCYAKARLWFHS
Uniprot:
P19397
Synonyms:
antigen MOX44 identified by monoclonal antibody MRC-OX44;CD53 antigen;CD53 glycoprotein;CD53 tetraspan antigen;cell surface antigen;cell surface glycoprotein CD53;leukocyte surface antigen CD53;MOX44;tetraspanin-25;transmembrane glycoprotein;tspan-25;TSPAN25
Extra Details:
The protein encoded by this gene is a member of the transmembrane 4 superfamily, also known as the tetraspanin family. Most of these members are cell-surface proteins that are characterized by the presence of four hydrophobic domains. The proteins mediate signal transduction events that play a role in the regulation of cell development, activation, growth and motility. This encoded protein is a cell surface glycoprotein that is known to complex with integrins. It contributes to the transduction of CD2-generated signals in T cells and natural killer cells and has been suggested to play a role in growth regulation. Familial deficiency of this gene has been linked to an immunodeficiency associated with recurrent infectious diseases caused by bacteria, fungi and viruses. Alternative splicing results in multiple transcript variants.
Shipping Conditions:
Blue Ice