[KO Validated] UBE2O Rabbit polyclonal antibody

Size

POA

SKU:: A10036
Additional Names:: 2O|E2-230K
Application:: ELISA, WB, IF, ICC, IP
Molecular Weight:: 200kDa
Species Reactivity:: Human
Purification:: Affinity Purified
Storage Conditions:: -20[o]C Avoid freeze/thaw cycles.
Supplier:: Abclonal
Host:: Rabbit
Reactivities:: Human, Mouse, Rat
Immunogen:: Recombinant protein (or fragment).This information is considered to be commercially sensitive.
Formulation:: Unmodified
Sequence:: LVNEPYYNEAGFDSDRGLQEGYENSRCYNEMALIRVVQSMTQLVRRPPEVFEQEIRQHFSTGGWRLVNRIESWLETHALLEKAQALPNGVPKASSSPEPPAVAELSDSGQQEPEDGGPAPGEASQGSDSEGGAQGLASASRDHTDQTSETAPDASVPPSVKPKKRRKSYRSFLPEKSGYPDIGFPLFPLSKGFIKSIRGVLTQFRAALLEAGMPECTEDK
Uniprot:: Q9C0C9
Synonyms:: (E3-independent) E2 ubiquitin-conjugating enzyme;E2-230K;E2/E3 hybrid ubiquitin-protein ligase UBE2O;ubiquitin carrier protein O;ubiquitin conjugating enzyme E2O;Ubiquitin-conjugating enzyme E2 O;ubiquitin-conjugating enzyme E2 of 230 kDa;ubiquitin-conjugating enzyme E2-230K;ubiquitin-protein ligase O
Extra Details:: Enables ubiquitin conjugating enzyme activity and ubiquitin protein ligase activity. Involved in positive regulation of BMP signaling pathway; protein ubiquitination; and retrograde transport, endosome to Golgi. Located in cytoplasm and nuclear body.