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A0936

MARCKS Rabbit polyclonal antibody

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£152.00

SKU:
A0936
Additional Names:
80K-L|MACS|MARCKS|PKCSL|PRKCSL
Application:
ELISA, WB, IF, ICC
Molecular Weight:
80 kDa
Species Reactivity:
Human
Purification:
Affinity Purified
Storage Conditions:
-20[o]C Avoid freeze/thaw cycles.
Supplier:
Abclonal
Host:
Rabbit
Reactivities:
Human, Mouse, Rat
Immunogen:
Synthetic peptide. This information is considered to be commercially sensitive.
Formulation:
Unmodified
Sequence:
MGAQFSKTAAKGEAAAERPGEAAVASSPSKANGQENGHVKVNGDASPAAAESGAKEELQANGSAPAADKEEPAAAGSGAASPSAAEKGEPAAAAAPEAGA
Uniprot:
P29966
Synonyms:
80K-L;MACS;myristoylated alanine-rich C-kinase substrate;myristoylated alanine-rich protein kinase C substrate (MARCKS, 80K-L);phosphomyristin;PKCSL;PRKCSL;protein kinase C substrate, 80 kDa protein, light chain
Extra Details:
The protein encoded by this gene is a substrate for protein kinase C. It is localized to the plasma membrane and is an actin filament crosslinking protein. Phosphorylation by protein kinase C or binding to calcium-calmodulin inhibits its association with actin and with the plasma membrane, leading to its presence in the cytoplasm. The protein is thought to be involved in cell motility, phagocytosis, membrane trafficking and mitogenesis.
Shipping Conditions:
Blue Ice