JAK3 Rabbit polyclonal antibody

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£152.00

SKU:: A0748
Additional Names:: JAK-3|JAK3|JAK3_HUMAN|JAKL|L-JAK|LJAK
Application:: ELISA, WB, IF, ICC
Molecular Weight:: 115kDa
Species Reactivity:: Human
Purification:: Affinity Purified
Storage Conditions:: -20[o]C Avoid freeze/thaw cycles.
Supplier:: Abclonal
Host:: Rabbit
Reactivities:: Human
Immunogen:: Recombinant protein (or fragment).This information is considered to be commercially sensitive.
Formulation:: Unmodified
Sequence:: RLTTDSQHFFCKEVAPPRLLEEVAEQCHGPITLDFAINKLKTGGSRPGSYVLRRSPQDFDSFLLTVCVQNPLGPDYKGCLIRRSPTGTFLLVGLSRPHSSLRELLATCWDGGLHVDGVAVTLTSCCIPRPKEKSNLIVVQRGHSPPTSSLVQPQSQYQLSQMTFHKIPADSLEWHENLGHG
Uniprot:: P52333
Synonyms:: JAK-3;JAK3_HUMAN;JAKL;Janus kinase 3;Janus kinase 3 (a protein tyrosine kinase, leukocyte);L-JAK;leukocyte Janus kinase;LJAK;tyrosine-protein kinase JAK3
Extra Details:: The protein encoded by this gene is a member of the Janus kinase (JAK) family of tyrosine kinases involved in cytokine receptor-mediated intracellular signal transduction. It is predominantly expressed in immune cells and transduces a signal in response to its activation via tyrosine phosphorylation by interleukin receptors. Mutations in this gene are associated with autosomal SCID (severe combined immunodeficiency disease).