UBE4A Rabbit monoclonal antibody

Size

POA

SKU:: A0710
Additional Names:: E4|NEDHMS|UBE4A|UBOX2|UFD2
Application:: ELISA, WB
Molecular Weight:: 125kDa
Species Reactivity:: Human
Purification:: Affinity Purified
Storage Conditions:: -20[o]C Avoid freeze/thaw cycles.
Supplier:: Abclonal
Host:: Rabbit
Reactivities:: Human
Immunogen:: Synthetic peptide. This information is considered to be commercially sensitive.
Formulation:: Unmodified
Sequence:: MTDQENNNNISSNPFAALFGSLADAKQFAAIQKEQLKQQSDELPASPDDSDNSVSESLDEFDYSVAEISRSFRSQQEICEQLNINHMIQRIFLITLDNSD
Uniprot:: Q14139
Synonyms:: E4;RING-type E3 ubiquitin transferase E4 A;ubiquitin conjugation factor E4 A;ubiquitination factor E4A (UFD2 homolog, yeast);UBOX2;UFD2
Extra Details:: This gene encodes a member of the U-box ubiquitin ligase family. The encoded protein is involved in multiubiquitin chain assembly and plays a critical role in chromosome condensation and separation through the polyubiquitination of securin. Autoantibodies against the encoded protein may be markers for scleroderma and Crohn's disease. A pseudogene of this gene is located on the long arm of chromosome 3. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.