SOX2 Rabbit polyclonal antibody

Size

£152.00

SKU:: A0561
Additional Names:: ANOP3|MCOPS3|SOX2
Application:: ELISA, WB, IHC-P, IF, ICC, IP
Molecular Weight:: 35 kDa
Species Reactivity:: Human
Purification:: Affinity Purified
Storage Conditions:: -20[o]C Avoid freeze/thaw cycles.
Supplier:: Abclonal
Host:: Rabbit
Reactivities:: Human, Mouse, Rat
ABP:: No Import Docs
Immunogen:: Recombinant protein (or fragment).This information is considered to be commercially sensitive.
Formulation:: Unmodified
Sequence:: MYNMMETELKPPGPQQTSGGGGGNSTAAAAGGNQKNSPDRVKRPMNAFMVWSRGQRRKMAQENPKMHNSEISKRLGAEWKLLSETEKRPFIDEAKRLRALHMKEHPDYKYRPRRKTKTLMKKDKYTLPGGLLAPGGNSMA
Uniprot:: P48431
Synonyms:: ANOP3;MCOPS3;sex determining region Y-box 2;SRY (sex determining region Y)-box 2;SRY-box 2;SRY-related HMG-box gene 2;transcription factor SOX-2;transcription factor SOX2
Extra Details:: This intronless gene encodes a member of the SRY-related HMG-box (SOX) family of transcription factors involved in the regulation of embryonic development and in the determination of cell fate. The product of this gene is required for stem-cell maintenance in the central nervous system, and also regulates gene expression in the stomach. Mutations in this gene have been associated with optic nerve hypoplasia and with syndromic microphthalmia, a severe form of structural eye malformation. This gene lies within an intron of another gene called SOX2 overlapping transcript (SOX2OT).