UBE4B Rabbit monoclonal antibody

Size

POA

SKU:: A0419
Additional Names:: E4|HDNB1|UBE4B|UBOX3|UFD2|UFD2A
Application:: ELISA, WB
Molecular Weight:: 146kDa
Species Reactivity:: Human
Purification:: Affinity Purified
Storage Conditions:: -20[o]C Avoid freeze/thaw cycles.
Supplier:: Abclonal
Host:: Rabbit
Reactivities:: Human, Mouse, Rat
Immunogen:: Synthetic peptide. This information is considered to be commercially sensitive.
Formulation:: Unmodified
Sequence:: MEELSADEIRRRRLARLAGGQTSQPTTPLTSPQRENPPGPPIAASAPGPSQSLGLNVHNMTPATSPIGASGVAHRSQSSEGVSSLSSSPSNSLETQSQSL
Uniprot:: O95155
Synonyms:: E4;HDNB1;homologous to yeast UFD2;Homozygously deleted in neuroblastoma 1;homozygously deleted in neuroblastoma-1;RING-type E3 ubiquitin transferase E4 B;ubiquitin conjugation factor E4 B;Ubiquitin fusion degradation protein 2;ubiquitin-fusion degradation protein 2;ubiquitination factor E4B (UFD2 homolog, yeast);UBOX3;UFD2;UFD2A
Extra Details:: The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes, or E1s, ubiquitin-conjugating enzymes, or E2s, and ubiquitin-protein ligases, or E3s. This gene encodes an additional conjugation factor, E4, which is involved in multiubiquitin chain assembly. This gene is also the strongest candidate in the neuroblastoma tumor suppressor genes. Alternatively spliced transcript variants encoding distinct isoforms have been found for this gene.

Shipping Conditions:: Blue Ice