RYR2 Rabbit polyclonal antibody

Size

£152.00

SKU:: A0298
Additional Names:: ARVC2|ARVD2|RyR|RYR-2|RYR2|VACRDS|VTSIP
Application:: ELISA, WB, IHC-P, IF
Molecular Weight:: 565 kDa
Species Reactivity:: Human
Purification:: Affinity Purified
Storage Conditions:: -20[o]C Avoid freeze/thaw cycles.
Supplier:: Abclonal
Host:: Rabbit
Reactivities:: Human, Mouse, Rat
Immunogen:: This information is considered to be commercially sensitive.
Formulation:: Unmodified
Sequence:: DAFGELRDQQEQVKEDMETKCFICGIGNDYFDTVPHGFETHTLQEHNLANYLFFLMYLINKDETEHTGQESYVWKMYQERCWEFFPAGDCFRKQYEDQLN
Uniprot:: Q92736
Synonyms:: ARVC2;ARVD2;Cardiac muscle ryanodine receptor;cardiac muscle ryanodine receptor-calcium release channel;cardiac-type ryanodine receptor;islet-type ryanodine receptor;kidney-type ryanodine receptor;ryanodine receptor 2;ryanodine receptor 2 (cardiac);RyR;RYR-2;type 2 ryanodine receptor;VACRDS;VTSIP
Extra Details:: This gene encodes a ryanodine receptor found in cardiac muscle sarcoplasmic reticulum. The encoded protein is one of the components of a calcium channel, composed of a tetramer of the ryanodine receptor proteins and a tetramer of FK506 binding protein 1B proteins, that supplies calcium to cardiac muscle. Mutations in this gene are associated with stress-induced polymorphic ventricular tachycardia and arrhythmogenic right ventricular dysplasia.