Interferon alpha 1 (IFN-A Alpha1) Rabbit polyclonal antibody

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£152.00

SKU:: A0285
Additional Names:: IFL|IFN|IFN-ALPHA|IFN-alphaD|IFNA@|IFNA13|Interferon alpha 1 (IFN-A Alpha1)|leIF D
Application:: ELISA, WB
Molecular Weight:: 18kDa/22kDa
Species Reactivity:: Human
Purification:: Affinity Purified
Storage Conditions:: -20[o]C Avoid freeze/thaw cycles.
Supplier:: Abclonal
Host:: Rabbit
Reactivities:: Human
Immunogen:: Recombinant protein (or fragment).This information is considered to be commercially sensitive.
Formulation:: Unmodified
Sequence:: CDLPETHSLDNRRTLMLLAQMSRISPSSCLMDRHDFGFPQEEFDGNQFQKAPAISVLHELIQQIFNLFTTKDSSAAWDEDLLDKFCTELYQQLNDLEACVMQEERVGETPLMNADSILAVKKYFRRITLYLTEKKYSPCAWEVVRAEIMRSLSLSTNLQERLRRKE
Uniprot:: P01562
Synonyms:: IFL;IFN;IFN-ALPHA;IFN-alpha-1/13;IFN-alphaD;IFNA@;IFNA13;interferon alpha 1b;interferon alpha-1/13;interferon alpha-D;interferon-alpha1;leIF D
Extra Details:: This gene is a member of the alpha interferon gene cluster on chromosome 9. The encoded cytokine is a member of the type I interferon family that is produced in response to viral infection as a key part of the innate immune response with potent antiviral, antiproliferative and immunomodulatory properties. This cytokine, like other type I interferons, binds a plasma membrane receptor made of IFNAR1 and IFNAR2 that is ubiquitously expressed, and thus is able to act on virtually all body cells. This cytokine is upregulated in preeclamptic placentas and is thought to be a mediator of preeclampsia.