MYH9 Rabbit polyclonal antibody

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£152.00

SKU:: A0173
Additional Names:: BDPLT6|DFNA17|EPSTS|FTNS|MATINS|MHA|MYH9|NMHC-II-A|NMMHC-IIA|NMMHCA
Application:: ELISA, WB, IHC-P
Molecular Weight:: 250 kDa
Species Reactivity:: Human
Purification:: Affinity Purified
Storage Conditions:: -20[o]C Avoid freeze/thaw cycles.
Supplier:: Abclonal
Host:: Rabbit
Reactivities:: Human, Mouse
Immunogen:: Recombinant protein (or fragment).This information is considered to be commercially sensitive.
Formulation:: Unmodified
Sequence:: ANSSGKGALALEEKRRLEARIAQLEEELEEEQGNTELINDRLKKANLQIDQINTDLNLERSHAQKNENARQQLERQNKELKVKLQEMEGTVKSKYKASITALEAKIAQLEEQLDNETKERQAACKQVRRTEKKLKDVLLQVDDERRNAEQYKDQADKASTRLKQLKRQLEEAEEEAQRANASRRKLQRELEDATETADAMNREVSSLKNKLRRGDLPFVVPRRMARKGAGDGSDEEVDGKADGAEAKPAE
Uniprot:: P35579
Synonyms:: BDPLT6;cellular myosin heavy chain, type A;DFNA17;EPSTS;FTNS;MATINS;MHA;Myosin heavy chain 9;Myosin heavy chain, non-muscle IIa;myosin-9;myosin, heavy chain 9, non-muscle;NMHC-II-A;NMMHC-IIA;NMMHCA;non-muscle myosin heavy chain 9;non-muscle myosin heavy chain A;non-muscle myosin heavy chain IIa;non-muscle myosin heavy polypeptide 9;nonmuscle myosin heavy chain II-A
Extra Details:: This gene encodes a conventional non-muscle myosin; this protein should not be confused with the unconventional myosin-9a or 9b (MYO9A or MYO9B). The encoded protein is a myosin IIA heavy chain that contains an IQ domain and a myosin head-like domain which is involved in several important functions, including cytokinesis, cell motility and maintenance of cell shape. Defects in this gene have been associated with non-syndromic sensorineural deafness autosomal dominant type 17, Epstein syndrome, Alport syndrome with macrothrombocytopenia, Sebastian syndrome, Fechtner syndrome and macrothrombocytopenia with progressive sensorineural deafness.

Shipping Conditions:: Blue Ice