Theralizumab Biosimilar - Research Grade
Product Sizes
1mg
ICH5023-1MG
5mg
ICH5023-5MG
10mg (2x5mg)
ICH5023-10MG
25mg
ICH5023-25MG
50mg
ICH5023-50MG
100mg
ICH5023-100MG
200mg
ICH5023-200MG
500mg
ICH5023-500MG
1g
ICH5023-1G
About this Product
- SKU:
- ICH5023
- Additional Names:
- TGN1412, CD28-SuperMAB, TAB08
- Application:
- Cell-based/Functional Assay
- CE/IVD:
- RUO
- Clonality:
- Recombinant Monoclonal
- Concentration:
- 5mg/ml
- Extra Details:
- Theralizumab GN1412 is a humanised monoclonal antibody that not only binds to, but is a strong agonist for, the CD28 receptor of the immune system’s T cells. CD28 is the co-receptor for the T cell receptor; It binds to receptors on the interacting partner in the reaction through one of its ligands (B7 family). It was withdrawn from development after inducing severe inflammatory reactions as well as chronic organ failure in the first-in-human study by PAREXEL in London in March 2006.
- Formulation:
- Sterile, preservative-free, solution in PBS. BSA and Azide free.
- Immunogen:
- CD28
- Isotype:
- Human IgG4
- Purity:
- >95% by SDS-PAGE
- Purification:
- This monoclonal antibody was purified using multi-step affinity chromatography methods such as Protein A or G depending on the species and isotype.
- Reactivities:
- Human
- Shipping Conditions:
- Blue Ice
- Specificity:
- Detects human CD28. This non-therapeutic antibody uses the same sequence as the therapeutic antibody Theralizumab.
- Storage Conditions:
- This biosimilar is stable when stored at 2-8°C. For longer term storage (> 3 months) it is recommended to store this antibody at -20°C or -70°C.
- Supplier:
- ichorbio
- Type:
- Antibodies:Monoclonal Antibody
- Shipping Costs:
- Free shipping to UK Customers
- Manufacturer's Data Sheet:https://ichor.bio/productpdf/print/index/url_key/theralizumab-biosimilar-research-grade/
