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Antibodies

Utomilumab Biosimilar - Research Grade

Product Sizes
1mg
ICH5014-1MG
5mg
ICH5014-5MG
10mg (2x5mg)
ICH5014-10MG
25mg
ICH5014-25MG
50mg
ICH5014-50MG
100mg
ICH5014-100MG
200mg
ICH5014-200MG
500mg
ICH5014-500MG
1g
ICH5014-1G
About this Product
SKU:
ICH5014
Additional Names:
4-1BB ligand receptor, T-cell antigen 4-1BB, Tnfrsf9, Ila, Ly63, CD137
Application:
Cell-based/Functional Assay
CE/IVD:
RUO
Clonality:
Recombinant Monoclonal
Concentration:
5mg/ml
Extra Details:
RUO Utomilumab is a fully-human IgG2 agonist mAb that selectively binds human 4-1BB/CD137, resulting in NF-κB activation and downstream cytokine production in cell lines and primary lymphocytes. Utomilumab can induce human leukocyte proliferation and has demonstrated significant antitumor activity as a single agent in human peripheral blood lymphocyte (PBL) SCID xenograft tumor models.
Formulation:
Sterile, preservative-free, solution in PBS. BSA and Azide free.
Immunogen:
4-1BB
Isotype:
Human IgG2-Lambda 2
Purity:
>95% by SDS-PAGE
Purification:
This monoclonal antibody was purified using multi-step affinity chromatography methods such as Protein A or G depending on the species and isotype.
Reactivities:
Human
Shipping Conditions:
Blue Ice
Specificity:
Detects human CD137. This non-therapeutic antibody uses the same sequence as the therapeutic antibody Utomilumab.
Storage Conditions:
This biosimilar is stable when stored at 2-8°C. For longer term storage (> 3 months) it is recommended to store this antibody at -20°C or -70°C.
Supplier:
ichorbio
Type:
Antibodies:Monoclonal Antibody
Shipping Costs:
Free shipping to UK Customers