Z-Phe-Tyr-CHO
Product Sizes
1 mg
10-3079-1MG
5 mg
10-3079-5MG
About this Product
- SKU:
- 10-3079
- Additional Names:
- SB-412515|Z-FY-CHO|Z-Phe-Tyr-Aldehyde
- CAS Number:
- 167498-29-5
- Extra Details:
- A potent and selective inhibitor of cathepsin L, IC50=0.85 nM 1 selective over cathepsin B and calpain II (IC50s=85.1 and 184 nM respectively). Suppresses osteoclastic pit formation at 1.5 nM and markedly inhibited parathyroid hormone-stimulated osteoclastic bone resorption.2 Also inhibits cathepsin K (Kis=0.052 and 1.57 nM for cat L and cat K respectively) and partially provides the basis for the finding that cathepsin K is the protease responsible for osteoclastic bone resorption.3 Provides partial protection against serum and potassium deprivation-induced neuronal death.4 Active in vivo.2
- Immunogen:
- Protease
- Molecular Weight:
- 446.50
- Physical State:
- Solid
- Purity:
- 98%
- Shipping Conditions:
- Ambient
- Storage Conditions:
- -20[o]C
- Supplier:
- Focus Biomolecules
- Type:
- Proteins, Peptides, Small Molecules & Other Biomolecules: Inhibitors
