Purified Anti-Human CD197 Antibody[G043H7], Functional Grade

Size

£80.10

Was £89.00

SKU:: E-AB-F11590
Additional Names:: EBI,CDw,BLR,EVI,CMKBR,CC-CKR,CCR,CCR7,BLR2,CC-CKR-7,CCR-7,CD197,CDw197,CMKBR7,EBI1,EVI1, EBI-1, BLR-2, CMKBR7
Application:: Flow Cytometry
Concentration:: >= 1 mg/ml
Purification:: protein a/g purified
Storage Conditions:: 2-8[o]C Avoid freeze/thaw cycles., -20[o]C Avoid freeze/thaw cycles.
Supplier:: Elabscience
Host:: Mouse
Reactivities:: Human
Buffer:: Sterile PBS, pH 7.2. < 1.0 EU per mg of the antibody as determined by the LAL method.
Immunogen:: Recombinant Human CD197 protein
Clone:: G043H7
Uniprot:: P32248
Synonyms:: BLR2;Bukitt's lymphoma receptor 2;C-C chemokine receptor type 7;CC chemokine receptor 7;CC-CKR-7;CCR-7;CD197;CDw197;chemokine (C-C motif) receptor 7;CMKBR7;EBI1;EBV-induced G protein-coupled receptor 1;Epstein-Barr virus induced gene 1;Epstein-Barr virus-induced G-protein coupled receptor 1;lymphocyte-specific G protein-coupled peptide receptor;MIP-3 beta receptor
Extra Details:: The protein encoded by this gene is a member of the G protein-coupled receptor family. This receptor was identified as a gene induced by the Epstein-Barr virus (EBV), and is thought to be a mediator of EBV effects on B lymphocytes. This receptor is expressed in various lymphoid tissues and activates B and T lymphocytes. It has been shown to control the migration of memory T cells to inflamed tissues, as well as stimulate dendritic cell maturation. The chemokine (C-C motif) ligand 19 (CCL19/ECL) has been reported to be a specific ligand of this receptor. Signals mediated by this receptor regulate T cell homeostasis in lymph nodes, and may also function in the activation and polarization of T cells, and in chronic inflammation pathogenesis. Alternative splicing of this gene results in multiple transcript variants. None (Azide-Free,Low Endotoxin) are perfectly suited to be used in culture or in vivo (for nonhuman studies) for functional assays blocking, neutralizing, activation or depletion where the presence of azide may damage cells or exogenous endotoxin may signal or activate cells.

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