Superoxide Dismustase
Product Sizes
1 KU
16-05-191504-1KU
0.1 mg
16-05-191504-0.1MG
10 KU
16-05-191504-10KU
30 KU
16-05-191504-30KU
About this Product
- SKU:
- 16-05-191504
- Additional Names:
- Cell Culture Media, In Vitro Diagnostics, Oxidative Sstress, amyotrophic lateral sclerosis , Pakinson's, Alzheimer's, Cardiovascular Disease, Inflammation, Cancer|SOD, erythrocuprein, hemocuprein, cytocuprein, superoxide:superoxide oxidoreductase
- Application:
- Tissue Culture
- Buffer:
- Lyophilized from 0.1 M potassium phosphate, pH 7.5
- CAS Number:
- 9054-89-1
- CE/IVD:
- RUO
- Extra Details:
- Superoxide dismutase (SOD) is a critical antioxidant enzyme present in nearly all living cells exposed to oxygen. It catalyzes the rapid conversion of superoxide radicals-harmful byproducts of cellular metabolism-into hydrogen peroxide and molecular oxygen, thereby protecting cells from oxidative damage. SOD achieves this through highly efficient redox cycling at its active site, which contains essential metal cofactors such as copper, zinc, manganese, or iron, depending on the SOD isoform. These metal ions facilitate electron transfer, enabling SOD to neutralize superoxide radicals at rates limited only by molecular diffusion. Functionally, SOD plays a vital role in cellular defense against oxidative stress, maintaining metabolic and mitochondrial integrity. Mutations in the SOD1 gene are linked to familial amyotrophic lateral sclerosis (ALS), while altered SOD activity is implicated in diseases such as Parkinson's, Alzheimer's, Down syndrome, cardiovascular disease, and various inflammatory and neurodegenerative disorders. Clinically, SOD and its recombinant forms are being explored for therapeutic applications in conditions characterized by oxidative stress, including cardiovascular disease, traumatic brain injury, cancer, dermatological disorders, and inflammatory diseases. SOD activity is also used as a biomarker for oxidative stress and tissue health in both research and clinical diagnostics.
- Formulation:
- Lyophilized from 0.1 M potassium phosphate, pH 7.5
- Molecular Weight:
- 16,000 Da
- Physical State:
- Lyophilized
- Purity:
- ≥95%
- Purification:
- Liquid Chromatography Methods
- Shipping Conditions:
- Blue Ice
- Source:
- Prepared from whole blood shown to be non reactive for HBsAg, anti-HCV, anti-HBc, and negative for anti-HIV 1 & 2 by FDA-required tests.
- Storage Conditions:
- Please refer to datasheet
- Supplier:
- Athens Research & Technology Inc.
- Type:
- Proteins, Peptides, Small Molecules & Other Biomolecules: Enzymes
