Saralasin
About this Product
- SKU:
- NR-170
- Additional Names:
- [Sar1,Val5, Ala8] angiotensin II|[Sar1,Val5, Ala8] angiotensin II, 34273-10-4,angiotensin II, hypertension, NR-170, NR170
- CAS Number:
- 34273-10-4
- Extra Details:
- Saralasin, also known as [Sar1,Val5, Ala8] angiotensin II is an angiotensin II analog with substitutions to the angiotensin II sequence of sarcosine at position 1, valine at position 5,and alanine at position 8. Saralasin is a partial agonist of the angiotensin II receptor, and is used to treat hypertension.
- Immunogen:
- Angiotensin receptors
- Molecular Weight:
- 912
- Physical State:
- Freeze dried solid
- Purity:
- >95%
- References:
- <p>Steinhausen et al (1986) Angiotensin II control of the renal microcirculation: effect of blockade by saralasin. Kidney Int. <strong>30</strong> 56 PMID: 3747343 </p><p>Thomas et al (1995) Saralasin suppresses arrhythmias in an isolated guinea-pig ventricular free wall model of simulated ischemia and reperfusion. J.Pharmacol.Exp.Ther. <strong>274</strong> 1379 PMID: 7562511 </p><p>Guimond et al (2014) Saralasin and Sarile Are AT2 Receptor Agonists. ACS Med. Chem. Lett. <strong>5</strong>(10) 1129 doi:10.1021/ml500278g</p>
- Sequence:
- Sar-Arg-Val-Tyr-Val-His-Pro-Ala-OH
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- Store desiccated, frozen and in the dark
- Size:
- 1 mg
- Supplier:
- Isca Biochemicals
- Type:
- Proteins, Peptides, Small Molecules & Other Biomolecules: Peptides
- Solubility:
- Soluble in dilute acid and physiological buffers
- Formula:
- C42H65N13O10
