SMC-418
LRP4 (Extracellular) Antibody, Clone N207/27
Eine Lieferung in diese Region ist nicht möglich.
- SKU:
- SMC-418
- Zusätzliche Namen:
- LRP4, LRP-4, LRP10, MEGF7, Low density lipoprotein receptor related protein 4, Multiple epidermal growth factor like domains 7, LDLR dan, LDLR, KIAA0816, Corin
- Anwendung:
- WB, IF, ICC
- Konzentration:
- 1 mg/ml
- Spezies-Reaktivität:
- Mouse
- Aufreinigung:
- Protein G Purified
- Lagerbedingungen:
- -20[o]C
- Hersteller:
- StressMarq Biosciences
- Host:
- Mouse
- Reaktivitäten:
- Human, Mouse, Rat
- Buffer:
- PBS pH7.4, 50% glycerol, 0.09% sodium azide
- Immunogen:
- Fusion protein amino acids 26- 350 (extracellular N-terminus) of mouse LTP4
- Klon:
- N207/27 (Formerly sold as S207-27)
- Uniprot:
- Q8VI56
- Synonyme:
- 6430526J12Rik;D230026E03;LDLR dan;low-density lipoprotein receptor-related protein 4;LRP-4;mdi;mdig;Megf7;multiple epidermal growth factor-like domains 7
- Weitere Details:
- LRP4 (Low-Density Lipoprotein Receptor-Related Protein 4) is a transmembrane receptor essential for neuromuscular junction formation and synaptic signaling. It acts as a co-receptor for agrin and MuSK, facilitating synapse development and maintenance. In the central nervous system, LRP4 influences astrocyte-neuron communication and synaptic plasticity. Mutations or autoantibodies targeting LRP4 are linked to myasthenia gravis and may contribute to cognitive dysfunction. Emerging evidence suggests LRP4 plays a role in neurodegenerative diseases by modulating synaptic integrity and glial function. Its involvement in both peripheral and central synaptic regulation positions LRP4 as a promising target for therapeutic intervention in neuromuscular and neurodegenerative disorders.
- Versandbedingungen:
- Blue Ice