SKT-205
Corticosterone EIA Kit
Eine Lieferung in diese Region ist nicht möglich.
- SKU:
- SKT-205
- Zusätzliche Namen:
- (11B Beta)-11,21-dihydroxypregn-4-ene-3,20-dione
- Physischer Zustand:
- Cell Culture Supernatant, Feces, Plasma, Serum, Urine
- Lagerbedingungen:
- 2-8[o]C, -20[o]C
- Hersteller:
- StressMarq Biosciences
- ABP:
- No Import Docs
- Immunogen:
- Corticosterone EIA Kit
- Format:
- Colorimetric
- Weitere Details:
- Corticosterone (C₂₁H₃₀O₄) is a glucocorticoid hormone secreted by the adrenal cortex in response to ACTH stimulation. It is the primary stress hormone in rodents and a precursor to aldosterone. In neuroscience research, corticosterone is widely used to model chronic stress and its effects on brain function. Elevated corticosterone levels have been shown to impair memory retrieval, alter sleep-wake cycles, and exacerbate neurodegenerative processes. In Parkinson's disease models, chronic corticosterone exposure increases alpha-synuclein phosphorylation and aggregation, particularly in the hypothalamus, and contributes to dopaminergic neuron loss. These findings highlight corticosterone's role in stress-induced neurotoxicity and its relevance in studying the pathophysiology of neurodegenerative and psychiatric disorders.
- Versandbedingungen:
- Blue Ice