XIB4035

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SKU:: SIH-646
Zusätzliche Namen:: (E)-N4-(7-chloro-2-(2-chlorostyryl)quinolin-4-yl)-N1,N1-diethylpentane-1,4-diamine, 3(H3PO4)
Molekulargewicht:: 750.4
Reinheit:: >98%
Quelle:: Synthetic
Lagerbedingungen:: -20[o]C
Hersteller:: StressMarq Biosciences
CAS Number:: 10023-54-8
Weitere Details:: XIB4035 is a small-molecule GFRA Alpha1 agonist and GDNF pathway modulator with neuroprotective and neuroregenerative activity. It activates RET signaling and promotes neurite outgrowth, mimicking key effects of the neurotrophic factor GDNF. The GDNF-GFRA Alpha1-RET pathway is highly relevant to neurodegeneration research. In a Parkinson's disease mouse model, RET was shown to be essential for the neuroprotective and neuroregenerative effects of GDNF, supporting the use of XIB4035 as a tool to study neuronal survival and repair mechanisms.