SIH-639
P7C3-A20
Eine Lieferung in diese Region ist nicht möglich.
- SKU:
- SIH-639
- Zusätzliche Namen:
- 3,6-Dibromo--fluoro-N-(3-methoxyphenyl)-9H-carbazole-9-propanamine
- Molekulargewicht:
- 506.2
- Reinheit:
- ≥98%
- Quelle:
- Synthetic
- Lagerbedingungen:
- -20[o]C
- Hersteller:
- StressMarq Biosciences
- CAS Number:
- 1235481-90-9
- Weitere Details:
- P7C3-A20 is a neuroprotective and pro-neurogenic small molecule that acts through stimulation of NAMPT, a key enzyme in neuronal NAD⁺ biosynthesis¹. This compound enhances neuronal survival and promotes endogenous repair mechanisms following traumatic brain injury (TBI)². In mouse models of chronic TBI, P7C3-A20 also repairs blood-brain barrier integrity, halts progressive neurodegeneration by reversing tau phorphorylation³, and restores cognitive function⁴. Beyond TBI, it demonstrates robust neuroprotective activity in models of hypoxic-ischemic encephalopathy⁵. Additionally, P7C3-A20 suppresses neuroinflammation and protects retinal ganglion cells from degeneration in a rat optic nerve crush model(6), highlighting its potential across multiple forms of CNS injury.
- Versandbedingungen:
- Ambient