SIH-633
CBA
Eine Lieferung in diese Region ist nicht möglich.
- SKU:
- SIH-633
- Zusätzliche Namen:
- 4-Chloro-2-[[2-(2-chlorophenoxy)acetyl]amino]benzoic acid; TRPM4-IN-5
- Molekulargewicht:
- 340.2
- Reinheit:
- >98%
- Quelle:
- Synthetic
- Lagerbedingungen:
- -20[o]C
- Hersteller:
- StressMarq Biosciences
- CAS Number:
- 351424-20-9
- Weitere Details:
- CBA is a selective blocker of TRPM4 channels (IC50 = 1.5 uM), with no activity at related TRP channels or other ion channels. It has demonstrated neuroprotective effects in models of glutamate-induced neuronal degeneration and experimental autoimmune encephalomyelitis, a model of multiple sclerosis. By modulating TRPM4 activity, CBA provides a valuable tool for investigating calcium-independent cation flux in neurons and glial cells, and its role in neuroinflammation and neurodegeneration. Its specificity and in vivo efficacy make it a promising candidate for therapeutic exploration in CNS disorders.
- Versandbedingungen:
- Ambient