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SIH-542

NSC59984

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SKU:
SIH-542
Zusätzliche Namen:
NSC59984, NSC-59984, NSC59984, MLS000737358, SMR000528276, (E)-1-(4-methylpiperazin-1-yl)-3-(5-nitrofuran-2-yl)prop-2-en-1-one, 803647-40-7, AC1NS9AU, CID 5356520, MLS000737358, 1-Methyl-4-[3-(5-nitro-2-furanyl)-1-oxo-2-propenyl]-piperazine, 1-(4-Methyl-1-piperazinyl)-3-(5-nitro-2-furanyl)-2-propen-1-one
Molekulargewicht:
265.3
Reinheit:
>98%
Quelle:
Synthetic
Lagerbedingungen:
-20[o]C
Hersteller:
StressMarq Biosciences
CAS Number:
803647-40-7
ABP:
No Import Docs
Weitere Details:
NSC59984 is a small molecule that restores wild-type p53 signaling in tumor cells by modulating the mutant p53/MDM2 pathway. Although its primary application is in oncology, the compound's ability to influence p53-mediated apoptosis and DNA repair pathways may have relevance in neurodegenerative disease models, where p53 dysregulation contributes to neuronal loss. Its selective cytotoxicity in cancer cells while sparing healthy cells also highlights its potential for targeted therapeutic development.
Versandbedingungen:
Ambient