SIH-495
AZD6244
Eine Lieferung in diese Region ist nicht möglich.
- SKU:
- SIH-495
- Zusätzliche Namen:
- Selumetinib, AZD6244, 6-(4-bromo-2-chloroanilino)-7-fluoro-N-(2-hydroxyethoxy)-3-methylbenzimidazole-5-carboxamide
- Molekulargewicht:
- 457.7
- Reinheit:
- ≥98%
- Quelle:
- Synthetic
- Lagerbedingungen:
- -20[o]C
- Hersteller:
- StressMarq Biosciences
- CAS Number:
- 606143-52-6
- ABP:
- No Import Docs
- Weitere Details:
- AZD6244 (also known as Selumetinib) is a selective MEK1 inhibitor that blocks the phosphorylation of ERK1/2, key components of the MAPK/ERK signaling pathway. While it has been extensively studied in oncology for its ability to suppress tumor growth, its modulation of MAPK signaling has implications for neuroscience. Dysregulation of the MAPK/ERK pathway is associated with neuroinflammation, synaptic dysfunction, and neuronal death in various neurodegenerative diseases. AZD6244's ability to modulate this pathway positions it as a potential therapeutic candidate for conditions such as Alzheimer's disease and multiple sclerosis. Its pharmacological profile and ability to cross the blood-brain barrier make it a compound of interest for translational neuroscience research.
- Versandbedingungen:
- Ambient