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SIH-472

Roscovitine

Eine Lieferung in diese Region ist nicht möglich.

SKU:
SIH-472
Zusätzliche Namen:
2-(R)-[[9-(1-Methylethyl)-6-[(phenylmethyl)amino]-9H-purin-2-yl]amino]-1-butanol, 6-Benzylamino-2-(R)-[(1-ethyl)-2-hydroxyethylamino]-9-isopropylpurine, 2(R)-(1-Ethyl-2-hydroxyethylamino)-6-benzylamino-9-isopropylpurine
Molekulargewicht:
354.4
Reinheit:
>99% (TLC and HPLC); NMR (Conforms)
Quelle:
Synthetic
Lagerbedingungen:
-20[o]C
Hersteller:
StressMarq Biosciences
CAS Number:
186692-46-6
ABP:
No Import Docs
Weitere Details:
Roscovitine is a potent and selective inhibitor of cyclin-dependent kinases (CDKs), particularly CDK1/cyclin B, CDK2, and CDK5/p35. In neurodegenerative disease research, Roscovitine is widely used to study CDK5, a kinase implicated in tau phosphorylation, synaptic dysfunction, and neuronal death. It also affects calcium channel gating and promotes neuronal growth, making it a valuable tool for investigating cell cycle re-entry, neuroprotection, and regeneration in models of Alzheimer's and other neurodegenerative disorders.
Versandbedingungen:
Ambient