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SIH-470

PP2

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SKU:
SIH-470
Zusätzliche Namen:
3-(4-chlorophenyl) 1-(1,1-dimethylethyl)-1H-pyrazolo[3,4-d]pyrimidin-4-amine
Molekulargewicht:
301.8
Reinheit:
>98%
Quelle:
Synthetic
Lagerbedingungen:
-20[o]C
Hersteller:
StressMarq Biosciences
CAS Number:
172889-27-9
ABP:
No Import Docs
Weitere Details:
PP2 is a selective inhibitor of Src-family tyrosine kinases, including Lck, FynT, and Hck. It potently inhibits phosphorylation of focal adhesion kinase (FAK) and displays high selectivity over ZAP-70 and JAK2. In neurodegenerative disease research, PP2 is used to investigate the role of Src kinases in synaptic signaling, neuroinflammation, and blood-brain barrier integrity. Its application extends to models of Alzheimer's and multiple sclerosis, where Src-mediated pathways influence neuronal survival and immune responses.
Versandbedingungen:
Ambient