SIH-437
CHIR99021
Eine Lieferung in diese Region ist nicht möglich.
- SKU:
- SIH-437
- Zusätzliche Namen:
- CT99021 , 6-[[2-[[4-(2,4-Dichlorophenyl)-5-(5-methyl-1H-imidazol-2-yl)-2-pyrimidinyl]amino]ethyl]amino]-3-pyridinecarbonitrile
- Molekulargewicht:
- 465.3
- Reinheit:
- ≥98%
- Quelle:
- Synthetic
- Lagerbedingungen:
- -20[o]C
- Hersteller:
- StressMarq Biosciences
- CAS Number:
- 252917-06-9
- ABP:
- No Import Docs
- Weitere Details:
- CHIR99021 is a potent and highly selective inhibitor of glycogen synthase kinase-3 (GSK-3), a serine/threonine kinase involved in numerous cellular processes. In neuroscience, GSK-3 is implicated in tau phosphorylation, synaptic plasticity, and neuroinflammation-key features of neurodegenerative diseases such as Alzheimer's and Parkinson's. CHIR99021 promotes B Beta-catenin stabilization and supports neural stem cell self-renewal and differentiation. It is widely used to study Wnt signaling, neurogenesis, and the therapeutic potential of GSK-3 inhibition in brain repair and neuroprotection.
- Versandbedingungen:
- Ambient